PCR is a very common scientific technique that has been widely used in research and medicine for around 20-30 years to detect genetic information. RT - PCR (REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION) whether a person had the disease, as it only detects when the active virus is present. Like RT-PCR, LAMP tests are highly sensitive and reliable if performed on a sample from an infected part of the body whilst an active infection is occurring. LAMP tests cannot detect if a person has had the virus and then cleared it after the end of the COVID-19 disease, i.e. LAMP is a newer technique compared to RT-PCR, but is technically simple and easy for a trained scientist to perform, making it a potentially useful technique for the detection of COVID19. The amount of DNA produced in LAMP is much higher than in RT-PCR and a positive test result can be seen visually without requiring a machine to read the results. (LAMP) is a similar process to RT-PCR, but instead of using a series of temperature changes to produce copies of the viral DNA, LAMP is conducted at a constant temperature of 60-65☌. LAMP (LOOP MEDIATED ISOTHERMAL AMPLIFICATION) These types of tests work very differently to RT-PCR and LAMP techniques and detect the patient's immune antibody response to the virus rather than detecting the virus itself. A major advantage for this type of test is also the ability to see if patients are currently infected or have recovered from COVID-19 even if they have fully recovered and cleared the virus months ago. They require a drop of patient blood, either from a vein or from a small finger prick, similar to a finger prick test used for blood sugar monitoring in certain types of diabetes. Less commonly, lateral flow tests can be used to detect the presence of active virus by detecting virus proteins directly. Lateral flow tests can detect antibody to virus from patient blood indicating that the patient has COVID-19 or has recovered from COVID-19. Lateral flow assays use the same technology commonly used for pregnancy tests. The technology is also being tested for antigen use too. Lateral flow assays have commonly been referred to as ‘Antibody tests’ in the media as they are currently used to detect antibodies to disease in a patient's blood. Please do remember that if you or a family member have coronavirus symptoms such as a high temperature, a new cough, or a change in your sense of taste or smell then you should first attempt to use a free NHS service before using ourselves.ĪNTIBODY TESTS - LATERAL FLOW/COLLOIDAL GOLD IMMUNOCHROMATOGRAPHY Welcome to Post Haste, we specialise in being able to offer you the right Covid Swab test for your needs - whether you need to provide you are covid free because you are going on holiday, are looking for a business solution for yourself, or need a whole corporate coronavirus testing package, we can help you find the right solution.
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